منابع مشابه
Brain response to protein undernutrition. Mechanism of preferential protein retention.
This study was designed to determine how the brain, in contrast to most other tissues, maintains an almost normal protein content during a period of dietary protein deficiency. Administration of leucine-(3)H to rats was started during a period of early development (6-18 days) which is characterized by disproportionately rapid brain growth; later (24-33 days) leucine-(14)C was administered, when...
متن کاملMaternal undernutrition and the ovine acute phase response to vaccination
BACKGROUND The acute phase response is the immediate host response to infection, inflammation and trauma and can be monitored by measuring the acute phase proteins (APP) such as haptoglobin (Hp) or serum amyloid A (SAA). The plane of nutrition during pregnancy is known to affect many mechanisms including the neuroendocrine and neuroimmune systems in neonatal animals but effects on the APP are u...
متن کاملClassification of protein-calorie undernutrition in children.
Since the first description of kwashiorkor by Williams (1935), this condition has been found to be prevalent in many economically backward countries. Nevertheless, the minimum criteria for the diagnosis of kwashiorkor have never been agreed. Brock and Autret (1952) accepted a diagnosis of kwashiorkor if there was retarded growth, alterations in skin and hair pigmentation, oedema, fatty infiltra...
متن کاملPerinatal undernutrition: accumulation of catecholamines in rat brain.
Brains of rats undernourished from midgestation and killed at weaning contained 25 percent less norepinephrine than brains of adequately fed littermates. Perinatal undernutrition also suppressed the accumulation of brain dopamine. Paradoxically, the activity of tyrosine hydroxylase, the enzyme thought to be rate-limiting in catecholamine biosynthesis, was significantly increased in brains from ...
متن کاملDoes Undernutrition during Infancy Inhibit Brain Growth and Subsequent Intellectual
Experiments at Cambridge have shown that undernutrition during the early period of growth of calves will result in a reduction in size of the mature animal even if a high level of feeding is subsequently given, whereas a similar period of undernutrition in the 2-year-old animal, which was well fed as a calf, has much less effect on the mature size (Brookes and Vincett, 1950). The slower maturin...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1972
ISSN: 0021-9738
DOI: 10.1172/jci107024